• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Activity: Immobilized Human IL-17C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RE, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA (QC Test). The affinity constant of 66.41 nM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Thr155-His454
Catalog #IL1-HM2RE
Price
Regular price $34650
Regular price Sale price $34650
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Size
Avantor VWR Fisher Scientific

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Human IL-17RE Protein (IL1-HM2RE) Summary

Product Description

 Recombinant Human IL-17RE Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Thr155-His454.

Product Background

 IL-17RE is an orphan receptor of the IL-17 receptor family. It is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection. IL-17RE is also identified as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.

Human IL-17RE Protein (IL1-HM2RE) Specifications/Details

Protein
 IL-17RE
Synonyms
 IL-17RE; IL17RE; UNQ3056/PRO9877;
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Thr155-His454
Molecular Weight
 The protein has a predicted MW of 60.02 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human IL-17C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RE, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA (QC Test). The affinity constant of 66.41 nM as determined in SPR assay (Biacore T200).
Product Tag
 C-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human IL-17C, hFc Tag immobilized on CM5 Chip can bind Human IL-17RE, hFc Tag with an affinity constant of 66.41 nM as determined in SPR assay (Biacore T200). Human IL-17C, hFc Tag immobilized on CM5 Chip can bind Human IL-17RE, hFc Tag with an affinity constant of 66.41 nM as determined in SPR assay (Biacore T200).
Immobilized Human IL-17C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RE, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA (QC Test). Immobilized Human IL-17C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RE, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA (QC Test).
Human IL-17RE on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-17RE on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-17RE is greater than 90% as determined by SEC-HPLC. The purity of Human IL-17RE is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
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