Human IL-18RAP Protein (IL8-HM1AP)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-18RAP, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Phe20-Arg356

Catalog: IL8-HM1AP

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Product Description Recombinant Human IL-18RAP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe20-Arg356.

Product Background

lactoferrin (LTF), peptidoglycan recognition protein 1 and IL-18 receptor accessory protein (IL-18RAP) remained significantly elevated in peripheral monocytes of hypertensive individuals in a separate validation cohort. Interestingly, IL18RAP expression associated with MAP in a cohort of African Americans..

Product Category

Recombinant Protein

Target

IL-18RAP
Synonyms ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB; IL18RAP; IL-18R-bet
Accession

Species

Human

Amino Acid Range

Phe20-Arg356
Molecular Weight The protein has a predicted MW of 39.3 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human IL-18RAP, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IL-18RAP, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA.
The purity of Human IL-18RAP is greater than 95% as determined by SEC-HPLC.
Human IL-18RAP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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