Human IL-18RAP Protein (IL8-HM1AP)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-18RAP, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Phe20-Arg356

Catalog: IL8-HM1AP

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Product Description	Recombinant Human IL-18RAP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe20-Arg356.
Product Background	lactoferrin (LTF), peptidoglycan recognition protein 1 and IL-18 receptor accessory protein (IL-18RAP) remained significantly elevated in peripheral monocytes of hypertensive individuals in a separate validation cohort. Interestingly, IL18RAP expression associated with MAP in a cohort of African Americans..
Product Category	Recombinant Protein

Target	IL-18RAP
Synonyms	ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB; IL18RAP; IL-18R-bet
Gene/Protein ID	O95256-1
Species	Human
Exact Sequence	Phe20-Arg356
Molecular Weight	The protein has a predicted MW of 39.3 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human IL-18RAP, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human IL-18RAP, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA.
	The purity of Human IL-18RAP is greater than 95% as determined by SEC-HPLC.
	Human IL-18RAP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.