Human IL-1F10/IL-38-Protein (ILF-HE138)

  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Met1-Trp152

Catalog: ILF-HE138

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Product Description Recombinant Human IL-1F10/IL-38-Protein is expressed from E.coli with His tag at the C-Terminus.It contains Met1-Trp152.

Product Background

Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways; thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells.

Product Category

Recombinant Protein

Target

IL-1F10/IL-38

Gene/Protein ID

AAK68048.1

Species

Human

Exact Sequence

Met1-Trp152
Molecular Weight The protein has a predicted MW of 18.64 kDa. The protein migrates to 20-25 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human IL-1F10 is greater than 95% as determined by SEC-HPLC.
Human IL-1F10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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