Human IL-1F10/IL-38-Protein (ILF-HE138)
Catalog: ILF-HE138
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| Product Description | Recombinant Human IL-1F10/IL-38-Protein is expressed from E.coli with His tag at the C-Terminus.It contains Met1-Trp152. |
Product Background |
Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways; thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells. |
Product Category |
Recombinant Protein |
Target |
IL-1F10/IL-38 |
Gene/Protein ID |
AAK68048.1 |
Species |
Human |
Exact Sequence |
Met1-Trp152 |
| Molecular Weight | The protein has a predicted MW of 18.64 kDa. The protein migrates to 20-25 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
E.coli |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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The purity of Human IL-1F10 is greater than 95% as determined by SEC-HPLC. |
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Human IL-1F10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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