Human IL-1R2/IL-1 RII/CD121b Protein (IL1-HM0R2)
Human IL-1R2/IL-1 RII/CD121b Protein (IL1-HM0R2)
  • Express System: HEK293
  • Product Tag: No Tag
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-1R2, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Phe14-Glu343
Catalog #IL1-HM0R2
Regular price $297.00
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Product Description

Recombinant Human IL-1R2/IL-1 RII/CD121b Protein is expressed from HEK293 without tag.It contains Phe14-Glu343.

Product Background

Interleukin (IL)-1 has been reported to be involved in the development of tuberculosis (TB). IL1R1 and IL1R2 encode a cytokine receptor that belongs to the IL-1 receptor family.IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Mastitis. Among its related pathways are Hematopoietic cell lineage and IL-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include interleukin-1 receptor activity and interleukin-1, type II, blocking receptor activity.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

IL-1R2/IL-1 RII/CD121b

Synonyms

IL-1R-2; IL-1RT-2; IL-1RT2; CDw121b; IL-1R-beta; CD121b; IL1RB; IL1R2; IL-1 RII; MGC47725; IL-1R-β

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Phe14-Glu343

Molecular Weight

The protein has a predicted MW of 37.78 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human IL-1R2, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

No Tag

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human IL-1R2, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test). Immobilized Human IL-1R2, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.31ug/ml determined by ELISA (QC Test).
Human IL-1R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-1R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-1R2 is greater than 95% as determined by SEC-HPLC. The purity of Human IL-1R2 is greater than 95% as determined by SEC-HPLC.

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