Human IL-1R2/IL-1 RII/CD121b Protein (IL1-HM0R2)
  • Express System: HEK293
  • Product Tag: No Tag
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-1R2, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.21ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Phe14-Glu343
Catalog #IL1-HM0R2
Regular price $270.00
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Product Description
Recombinant Human IL-1R2/IL-1 RII/CD121b Protein is expressed from HEK293 without tag.It contains Phe14-Glu343.
Product Background
Interleukin (IL)-1 has been reported to be involved in the development of tuberculosis (TB). IL1R1 and IL1R2 encode a cytokine receptor that belongs to the IL-1 receptor family.IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Mastitis. Among its related pathways are Hematopoietic cell lineage and IL-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include interleukin-1 receptor activity and interleukin-1, type II, blocking receptor activity.
Product Category
Recombinant Protein
Target
IL-1R2/IL-1 RII/CD121b
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Phe14-Glu343
Molecular Weight
The protein has a predicted MW of 37.78 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human IL-1R2, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.21ug/ml determined by ELISA. See testing image for detail.
Product Tag
No Tag
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IL-1R2, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 0.21ug/ml determined by ELISA.
Human IL-1R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-1R2 is greater than 95% as determined by SEC-HPLC.

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