Name: Human IL-1R2/IL-1 RII/CD121b Protein (IL1-HM1R2)
Brand: KactusBio
SKU: IL1-HM1R2-100UG
Price: 210.0 USD
Availability: InStock

Human IL-1R2/IL-1 RII/CD121b Protein (IL1-HM1R2)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human IL-1R2, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 30.9ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Phe14-Glu343

Catalog #IL1-HM1R2

Size

100UG

500UG

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Product Description	Recombinant Human IL-1R2/IL-1 RII/CD121b Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe14-Glu343.
Product Background	Interleukin (IL)-1 has been reported to be involved in the development of tuberculosis (TB). IL1R1 and IL1R2 encode a cytokine receptor that belongs to the IL-1 receptor family.IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Mastitis. Among its related pathways are Hematopoietic cell lineage and IL-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include interleukin-1 receptor activity and interleukin-1, type II, blocking receptor activity.
Product Category	Recombinant Protein

Target	IL-1R2/IL-1 RII/CD121b
Synonyms	IL-1R-2; IL-1RT-2; IL-1RT2; CDw121b; IL-1R-beta; CD121b; IL1RB; IL1R2; IL-1 RII; MGC47725
Accession	NP_004624.1
Species	Human
Biotinylated	no
Amino Acid Range	Phe14-Glu343
Molecular Weight	The protein has a predicted MW of 38.9 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-1R2, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 30.9ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human IL-1R2, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 30.9ng/ml determined by ELISA.
	Human IL-1R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-1R2 is greater than 90% as determined by SEC-HPLC.

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