Name: Human IL-1RL1/ST2 Protein (ST2-HM2L1)
Brand: KactusBio
SKU: ST2-HM2L1-100UG
Price: 135.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-33, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-1RL1, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Lys19-Phe328

Catalog #ST2-HM2L1

Size

100UG

500UG

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Product Description	Recombinant Human IL-1RL1/ST2 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Lys19-Phe328.
Product Background	IL1RL1(also known as ST2)-is a member of the IL1-receptor family-and serves as the receptor for IL-33. The-ST2 protein-has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect. ST2/IL-33 signaling may play an important role in intestinal disease.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-1RL1/ST2
Synonyms	IL1RL1; DER4; ST2; T1; FIT-1; IL33R; ST2L; ST2V; IL-1 R4; IL1R4; Ly84; MGC32623
Accession	Q01638-2
Species	Human
Biotinylated	no
Amino Acid Range	Lys19-Phe328
Molecular Weight	The protein has a predicted MW of 61.75 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-33, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-1RL1, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-33, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-1RL1, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).
	Human IL-1RL1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-1RL1 is greater than 95% as determined by SEC-HPLC.