Human IL-1RL1/ST2 Protein (ST2-HM2L1)
Human IL-1RL1/ST2 Protein (ST2-HM2L1)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-33, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-1RL1, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Lys19-Phe328
Catalog #ST2-HM2L1
Regular price $135.00
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Product Description
Recombinant Human IL-1RL1/ST2 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Lys19-Phe328.
Product Background
IL1RL1(also known as ST2)-is a member of the IL1-receptor family-and serves as the receptor for IL-33. The-ST2 protein-has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect. ST2/IL-33 signaling may play an important role in intestinal disease.
Product Category
Recombinant Protein
Target
IL-1RL1/ST2
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Lys19-Phe328
Molecular Weight
The protein has a predicted MW of 61.75 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human IL-33, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-1RL1, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IL-33, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-1RL1, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).
Human IL-1RL1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-1RL1 is greater than 95% as determined by SEC-HPLC.

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