Human IL-2 R gamma/CD132 Protein (CD1-HM432)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Leu23-Asn254

Catalog: CD1-HM432

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Product Description Recombinant Human IL-2 R gamma/CD132 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu23-Asn254.

Product Background

 The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.

Product Category

 Recombinant Protein

Target

 IL-2 R gamma/CD132
Synonyms CD132; CIDX; IL-2 R gamma; IL2RG; IMD4; P64; SCIDX; SCIDX1; gammaC

Gene/Protein ID

 P31785-1

Species

 Human

Exact Sequence

 Leu23-Asn254
Molecular Weight The protein has a predicted MW of 39.9 kDa. Due to glycosylation, the protein migrates to 58-70 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His-Avi

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human IL-2 R gamma is greater than 95% as determined by SEC-HPLC.
Human IL-2 R gamma on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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