Name: Human IL-22 Protein (IL2-HM122)
Brand: KactusBio
SKU: IL2-HM122-100UG
Price: 330.0 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human IL-22, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala34-Ile179

Catalog #IL2-HM122

Size

100UG

500UG

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Product Description	Recombinant Human IL-22 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ala34-Ile179.
Product Background	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-22
Synonyms	Interleukin-22; IL-22; Cytokine Zcyto18; IL-TIF; IL-D110; TIFa; TIFIL-23; ZCYTO18
Accession	Q9GZX6
Species	Human
Biotinylated	no
Amino Acid Range	Ala34-Ile179
Molecular Weight	The protein has a predicted MW of 17.8 kDa. Due to glycosylation, the protein migrates to 28-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-22, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-22, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.
	Human IL-22 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human IL-22R alpha 1, hFc Tag on ProA-Biosensor can bind Human IL-22, His Tag with an affinity constant of 42.60 nM as determined in BLI assay (Gator® Prime).