Human IL-22R alpha 1 Protein (ILR-HM122)
Human IL-22R alpha 1 Protein (ILR-HM122)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-22R alpha 1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-22R alpha 1 Antibody, hFc Tag with the EC50 of 6.4ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: His16-Thr228
Catalog #ILR-HM122
Regular price $375.00
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Product Description
Recombinant Human IL-22R alpha 1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains His16-Thr228.
Product Background
IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Product Category
Recombinant Protein
Target
IL-22R alpha 1
Synonyms
IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11
Accession
Species
Human
Biotinylated
no
Amino Acid Range
His16-Thr228
Molecular Weight
The protein has a predicted MW of 25.67 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human IL-22R alpha 1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-22R alpha 1 Antibody, hFc Tag with the EC50 of 6.4ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human IL-22R alpha 1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-22R alpha 1 Antibody, hFc Tag with the EC50 of 6.4ng/ml determined by ELISA (QC Test).
Human IL-22R alpha 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-22R alpha 1 is greater than 95% as determined by SEC-HPLC.

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