Human IL-23 P19/IL-23A-Protein (IL2-HM219) Summary
Product Description |
Recombinant Human IL-23 P19/IL-23A-Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Arg20-Pro189. |
Product Background |
IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by inducing the expansion of CD4(+) cells producing IL-17. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human IL-23 P19/IL-23A-Protein (IL2-HM219) Specifications/Details
Protein |
IL-23 P19/IL-23A |
Synonyms |
IL-23 P19; IL-23A; IL-23-A; IL-23p19; IL23p19; SGRF |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Arg20-Pro189 |
Molecular Weight |
The protein has a predicted MW of 45.43 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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