Human IL-3 R Beta/CD131 Protein (IL3-HM1RB)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Thr17-Trp443

Catalog: IL3-HM1RB

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Product Description Recombinant Human IL-3 R Beta/CD131 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Thr17-Trp443.

Product Background

Interleukin-3 receptor (IL-3R) is a heterodimer that comprises an IL-3 specific alpha chain (IL-3R alpha) and a common beta chain (beta C) that is shared with the receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-5. The beta c subunit does not bind any cytokine by itself but is involved in the formation of high-affinity functional receptors for IL-5 and GM-CSF. These receptors belong to the cytokine receptor superfamily, but they are structurally and functionally more related to each other and thus make up a distinct subfamily.

Product Category

Recombinant Protein

Target

IL-3 R Beta/CD131

Gene/Protein ID

P32927-1

Species

Human

Exact Sequence

Thr17-Trp443
Molecular Weight The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human IL-3 R Beta is greater than 95% as determined by SEC-HPLC.
Human IL-3 R Beta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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