Human IL-36 alpha/IL-1F6 Protein (ILA-HE036) Summary
Product Description |
Recombinant Human IL-36 alpha/IL-1F6 Protein is expressed from E.coli without tag.It contains Lys6-Phe158. |
Product Background |
Within the IL-1 superfamily, IL-36 plays a pivotal role in both innate and adaptive immune responses. Of the four IL-36 isoforms, three have agonist activity (IL-36α, IL-36β, IL-36γ) and the fourth has antagonist activity (IL-36 receptor antagonist [IL-36Ra]). All IL-36 isoforms bind to the IL-36 receptor (IL-36R). Binding of IL-36α/β/γ to the IL-36R recruits the IL-1 receptor accessory protein (IL-1RAcP) and activates downstream signalling pathways mediated by nuclear transcription factor kappa B and mitogen-activated protein kinase signalling pathways. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human IL-36 alpha/IL-1F6 Protein (ILA-HE036) Specifications/Details
Protein |
IL-36 alpha/IL-1F6 |
Synonyms |
FIL1 epsilon; IL-1 epsilon; IL-1F6; IL36A; FIL1E; IL1E; IL1F6 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Lys6-Phe158 |
Molecular Weight |
The protein has a predicted MW of 17.11 kDa same as Bis-Tris PAGE result. |
Product Tag |
No Tag |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 100mM NaCl, 1mM TCEP, 0.02% Tween-20 (pH 8.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed