Human IL-36 alpha/IL-1F6 Protein (ILA-HE036)
  • Express System: E.coli
  • Product Tag: No Tag
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Lys6-Phe158
Catalog #ILA-HE036
Regular price $375.00
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Human IL-36 alpha/IL-1F6 Protein (ILA-HE036) Summary

Product Description

Recombinant Human IL-36 alpha/IL-1F6 Protein is expressed from E.coli without tag.It contains Lys6-Phe158.

Product Background

Within the IL-1 superfamily, IL-36 plays a pivotal role in both innate and adaptive immune responses. Of the four IL-36 isoforms, three have agonist activity (IL-36α, IL-36β, IL-36γ) and the fourth has antagonist activity (IL-36 receptor antagonist [IL-36Ra]). All IL-36 isoforms bind to the IL-36 receptor (IL-36R). Binding of IL-36α/β/γ to the IL-36R recruits the IL-1 receptor accessory protein (IL-1RAcP) and activates downstream signalling pathways mediated by nuclear transcription factor kappa B and mitogen-activated protein kinase signalling pathways.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human IL-36 alpha/IL-1F6 Protein (ILA-HE036) Specifications/Details

Protein
IL-36 alpha/IL-1F6
Synonyms
FIL1 epsilon; IL-1 epsilon; IL-1F6; IL36A; FIL1E; IL1E; IL1F6
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Lys6-Phe158
Molecular Weight
The protein has a predicted MW of 17.11 kDa same as Bis-Tris PAGE result.

Product Tag

No Tag
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 20mM Tris, 100mM NaCl, 1mM TCEP, 0.02% Tween-20 (pH 8.0).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human IL-36 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-36 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-36 alpha is greater than 95% as determined by SEC-HPLC. The purity of Human IL-36 alpha is greater than 95% as determined by SEC-HPLC.
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