Human IL-4 R alpha/CD124 Protein (ILA-HM14R)
Catalog: ILA-HM14R
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Product Description | Recombinant Human IL-4 R alpha/CD124 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-His232. |
Product Background |
Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells. |
Product Category |
Recombinant Protein |
Target |
IL-4 R alpha/CD124 |
Synonyms | CD124; IL-4 R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124 |
Gene/Protein ID |
P24394-1 |
Species |
Human |
Exact Sequence |
Gly24-His232 |
Molecular Weight | The protein has a predicted MW of 24.7 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human IL-4 R alpha, His Tag at 1ug/ml (100ul/Well). Dose response curve for Biotinylated Human IL-4, His Tag with the EC50 of 6.1ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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