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Human IL-5 R alpha/CD125 Protein (IL5-HM22R) Summary
Product Description |
Recombinant Human IL-5 R alpha/CD125 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-terminus.It contains Asp21-Trp342. |
Product Background |
Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human IL-5 R alpha/CD125 Protein (IL5-HM22R) Specifications/Details
Protein |
IL-5 R alpha/CD125 |
Synonyms |
CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asp21-Trp342 |
Molecular Weight |
The protein has a predicted MW of 62.73 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human IL-5, His Tag (Cat. IL5-HM101) at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-5 R alpha, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA. |
Product Tag |
N-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Human IL-5, His Tag (Cat. IL5-HM101) at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-5 R alpha, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA. |
|
|
Human IL-5 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human IL-5 R alpha is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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