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Human IL-7 R alpha/CD127 Protein (IL7-HM2RD) Summary
Product Description |
Recombinant Human IL-7 R alpha/CD127 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ala131-Asp239. |
Product Background |
Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human IL-7 R alpha/CD127 Protein (IL7-HM2RD) Specifications/Details
Protein |
IL-7 R alpha/CD127 |
Synonyms |
IL-7R alpha; IL7Ra; CD127; CDW127; IL7Rα |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala131-Asp239 |
Molecular Weight |
The protein has a predicted MW of 38.84 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
Other Available Proteins:
Finding available proteins...
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