• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Ala131-Asp239
Catalog #IL7-HM2RD
Price
Regular price $37500
Regular price Sale price $37500
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Size
Avantor VWR Fisher Scientific

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Human IL-7 R alpha/CD127 Protein (IL7-HM2RD) Summary

Product Description

 Recombinant Human IL-7 R alpha/CD127 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ala131-Asp239.

Product Background

 Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.

Human IL-7 R alpha/CD127 Protein (IL7-HM2RD) Specifications/Details

Protein
 IL-7 R alpha/CD127
Synonyms
 IL-7R alpha; IL7Ra; CD127; CDW127; IL7Rα;IL7R alpha
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ala131-Asp239
Molecular Weight
 The protein has a predicted MW of 38.84 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result.
Product Tag
 C-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...