Name: Human IL-7 R alpha/CD127 Protein (IL7-HM2RA)
Brand: KactusBio
SKU: IL7-HM2RA-100UG
Price: 247.5 USD
Availability: InStock

Human IL-7 R alpha/CD127 Protein (IL7-HM2RA)

Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7 R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested).

Human IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-7 R alpha is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7 R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested).
Amino Acid Range: Glu21-Gly236

Catalog #IL7-HM2RA

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human IL-7 R alpha/CD127 Protein (IL7-HM2RA) Summary

Product Description	Recombinant Human IL-7 R alpha/CD127 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu21-Gly236.
Product Background	Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human IL-7 R alpha/CD127 Protein (IL7-HM2RA) Specifications/Details

Protein	IL-7 R alpha/CD127
Synonyms	IL-7R alpha; IL7Ra; CD127; CDW127; IL7Rα
Accession	P16871-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Gly236
Molecular Weight	The protein has a predicted MW of 51.6 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7 R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested).
Product Tag	C-hFc (IgG1)
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7 R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested).
	Human IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-7 R alpha is greater than 95% as determined by SEC-HPLC.