Name: Human IL-7R alpha/CD127 Protein (IL7-HM2RA)
Brand: KactusBio
SKU: IL7-HM2RA-100UG
Price: 225.0 USD
Availability: InStock

Human IL-7R alpha/CD127 Protein (IL7-HM2RA)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested). See testing image for detail.
Amino Acid Range: Glu21-Gly236

Catalog #IL7-HM2RA

Size

100UG

500UG

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Product Description	Recombinant Human IL-7R alpha/CD127 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu21-Gly236.
Product Background	Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.
Product Category	Recombinant Protein

Target	IL-7R alpha/CD127
Synonyms	IL-17R alpha; IL7Ra; CD127; CDW127; ILRA
Accession	P16871-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Gly236
Molecular Weight	The protein has a predicted MW of 51.6 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested). See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested).
	Human IL-7R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-7R alpha is greater than 95% as determined by SEC-HPLC.

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