Human ILDR2 Protein (ILD-HM202)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 92% as determined by HPLC
  • Exact Sequence: Leu21-Met184

Catalog: ILD-HM202

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Product Description Recombinant Human ILDR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.

Product Background

 Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.

Product Category

 Recombinant Protein

Target

 ILDR2
Synonyms ILDR2; C1orf32; dJ782G3.1; RP4-782G3.2

Gene/Protein ID

 Q71H61

Species

 Human

Exact Sequence

 Leu21-Met184
Molecular Weight The protein has a predicted MW of 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.

Product Tag

 C-hFc

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 92% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human ILDR2 is greater than 92% as determined by SEC-HPLC.
Human ILDR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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