Name: Human ILDR2 Protein (ILD-HM202)
Brand: KactusBio
SKU: ILD-HM202-100UG
Price: 375.0 USD
Availability: InStock

Catalog #ILD-HM202

Size

100UG

500UG

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Product Description	Recombinant Human ILDR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.
Product Background	Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.
Product Category	Recombinant Protein / Antibody discovery

Protein	ILDR2
Synonyms	ILDR2; C1orf32; dJ782G3.1; RP4-782G3.2
Accession	Q71H61
Species	Human
Biotinylated	no
Amino Acid Range	Leu21-Met184
Molecular Weight	The protein has a predicted MW of 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human ILDR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ILDR2 is greater than 90% as determined by SEC-HPLC.