Product Description |
Recombinant Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe23-Ser1122(ITGA10) acidic tail & Gln21-Asp728(ITGB1) basic tail. |
Product Background |
Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts. |
Product Category |
Recombinant Protein |
Target |
Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer |
Synonyms |
Integrin alpha 10 beta 1; ITGA10&ITGB1; α10β1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Phe23-Ser1122(ITGA10) acidic tail & Gln21-Asp728(ITGB1) basic tail |
Molecular Weight |
The protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA10) and 100-130 kDa (ITGB1) based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human ITGA10&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
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