Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein (ITG-HM110)
Catalog: ITG-HM110
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| Product Description | Recombinant Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail. |
Product Background |
Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts. |
Product Category |
Recombinant Protein |
Target |
Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer |
Gene/Protein ID |
O75578-1(ITGA10)&P05556-1(ITGB1) |
Species |
Human |
Exact Sequence |
Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail |
| Molecular Weight | The protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA10) and 100-130 kDa (ITGB1) based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 90% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Human ITGA10&ITGB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%. |
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