Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein (ITG-HM110)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 90% as determined by Tris-Bis PAGE
  • Exact Sequence: Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail

Catalog: ITG-HM110

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Product Description Recombinant Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail.

Product Background

Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts.

Product Category

Recombinant Protein

Target

Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer

Gene/Protein ID

O75578-1(ITGA10)&P05556-1(ITGB1)

Species

Human

Exact Sequence

Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail
Molecular Weight The protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA10) and 100-130 kDa (ITGB1) based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 90% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human ITGA10&ITGB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

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