Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein (ITG-HM18B)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail
Catalog #ITG-HM18B
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Product Description
 Recombinant Human Integrin alpha 8 beta 1 (ITGA8&ITGB1)-Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail.
Product Background
 Human Integrin alpha 8 beta 1 is a heterodimeric glycoprotein composed of integrin alpha 8 and integrin beta 1 that mainly expressed in smooth muscle cells. It functions as a receptor for Tenascin, Fibronectin, and Vitronectin and can promote attachment, cell spreading, and neurite outgrowth.
Product Category
 Recombinant Protein
Target
 Integrin alpha 8 beta 1 (ITGA8&ITGB1) -Heterodimer
Synonyms
 ITGA8&ITGB1; ; α8β1; Integrin alpha 8 beta 1;
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail
Molecular Weight
 The protein has a predicted MW of 113.90 kDa (ITGA8) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 120-140 kDa (ITGA8) and 100-120 kDa (ITGB1) based on Bis-Tris PAGE result.
Product Tag
 C-His
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human ITGA8&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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