Product Description |
Recombinant Human Integrin alpha 8 beta 1 (ITGA8&ITGB1)-Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail. |
Product Background |
Human Integrin alpha 8 beta 1 is a heterodimeric glycoprotein composed of integrin alpha 8 and integrin beta 1 that mainly expressed in smooth muscle cells. It functions as a receptor for Tenascin, Fibronectin, and Vitronectin and can promote attachment, cell spreading, and neurite outgrowth. |
Product Category |
Recombinant Protein |
Target |
Integrin alpha 8 beta 1 (ITGA8&ITGB1) -Heterodimer |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail |
Molecular Weight |
The protein has a predicted MW of 113.90 kDa (ITGA8) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 120-140 kDa (ITGA8) and 100-120 kDa (ITGB1) based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human ITGA8&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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