Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein (ITG-HM18B)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail
Catalog #ITG-HM18B
Regular price $412.50
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Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein (ITG-HM18B) Summary

Product Description

Recombinant Human Integrin alpha 8 beta 1 (ITGA8&ITGB1)-Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA8.It contains Phe39-Leu1012(ITGA8) acidic tail and Gln21-Asp728(ITGB1) basic tail.

Product Background

Human Integrin alpha 8 beta 1 is a heterodimeric glycoprotein composed of integrin alpha 8 and integrin beta 1 that mainly expressed in smooth muscle cells. It functions as a receptor for Tenascin, Fibronectin, and Vitronectin and can promote attachment, cell spreading, and neurite outgrowth.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein (ITG-HM18B) Specifications/Details

Protein
Integrin alpha 8 beta 1 (ITGA8&ITGB1) -Heterodimer
Synonyms
ITGA8&ITGB1; ; α8β1; Integrin alpha 8 beta 1;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail
Molecular Weight
The protein has a predicted MW of 113.90 kDa (ITGA8) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 120-140 kDa (ITGA8) and 100-120 kDa (ITGB1) based on Bis-Tris PAGE result.
Product Tag
C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human ITGA8&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ITGA8&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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