Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein (ITG-HM4V8)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human ITGAV&ITGB8, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.39ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail

Catalog: ITG-HM4V8

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Product Description Recombinant Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminal.It contains Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail.
Product Category Recombinant Protein
Target Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer
Synonyms Integrin alpha V beta 8; TGAV&ITGB8
Gene/Protein ID P06756-1(ITGAV)&P26012-1(ITGB8)
Species Human
Exact Sequence Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail
Molecular Weight The protein has a predicted MW of 114 kDa (ITGAV)&76 kDa (ITGB8). Due to glycosylation, the protein migrates to 90-150 kDa based on Tris-Bis PAGE result.
Activity Immobilized Human ITGAV&ITGB8, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.39ug/ml determined by ELISA. See testing image for detail.
Product Tag C-His-Avi
Express System HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human ITGAV&ITGB8, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 0.39ug/ml determined by ELISA.
The purity of Human ITGAV&ITGB8 is greater than 95% as determined by SEC-HPLC.
Human ITGAV&ITGB8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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