Name: Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)
Brand: KactusBio
SKU: ITG-HM1XB-100UG
Price: 412.5 USD
Availability: InStock

Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)

Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).

Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).
Amino Acid Range: Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail

Catalog #ITG-HM1XB

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB) Summary

Product Description	Recombinant Human Integrin alpha X beta 2(ITGAX&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAX.It contains Phe20-Pro1107(ITGAX) acidic tail and Gln23-Asn700(ITGB2) basic tail.
Product Background	The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of alpha X beta 2 on dendritic cells and on other leukocytes, suggests a role in the immune response.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB) Specifications/Details

Protein	Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer
Synonyms	αXβ2; CD11C; SLEB6; CD18; ITGAX&ITGB2; ITGA; ITGB2
Accession	P20702-1(ITGAX)&P05107-1(ITGB2)
Species	Human
Biotinylated	no
Amino Acid Range	Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail
Molecular Weight	The protein has a predicted MW of 125.50 kDa (ITGAX) and 79.50 kDa (ITGB2). Due to glycosylation, the protein migrates to 130-135 kDa (ITGAX) and 85-95 kDa (ITGB2) based on Bis-Tris PAGE result.
Activity	Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).
	Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC.