Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)
Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)
Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail
Catalog #ITG-HM1XB
Regular price $375.00
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Product Description

Recombinant Human Integrin alpha X beta 2(ITGAX&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail.

Product Background

The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of alpha X beta 2 on dendritic cells and on other leukocytes, suggests a role in the immune response.

Product Category

Recombinant Protein / Antibody discovery

Protein

Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer

Synonyms

αXβ2; CD11C; SLEB6; CD18; ITGAX&ITGB2; ITGA; ITGB2

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail

Molecular Weight

The protein has a predicted MW of 125.50 kDa (ITGAX) and 79.50 kDa (ITGB2). Due to glycosylation, the protein migrates to 130-135 kDa (ITGAX) and 85-95 kDa (ITGB2) based on Bis-Tris PAGE result.

Activity

Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test). Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).
Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC. The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC.

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