Name: Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)
Brand: KactusBio
SKU: ITG-HM1XB-100UG
Price: 375.0 USD
Availability: InStock

Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein (ITG-HM1XB)

Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).

Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail

Catalog #ITG-HM1XB

Size

100UG

500UG

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Product Description	Recombinant Human Integrin alpha X beta 2(ITGAX&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail.
Product Background	The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of alpha X beta 2 on dendritic cells and on other leukocytes, suggests a role in the immune response.
Product Category	Recombinant Protein / Antibody discovery

Protein	Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer
Synonyms	αXβ2; CD11C; SLEB6; CD18; ITGAX&ITGB2; ITGA; ITGB2
Accession	P20702-1(ITGAX)&P05107-1(ITGB2)
Species	Human
Biotinylated	no
Amino Acid Range	Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail
Molecular Weight	The protein has a predicted MW of 125.50 kDa (ITGAX) and 79.50 kDa (ITGB2). Due to glycosylation, the protein migrates to 130-135 kDa (ITGAX) and 85-95 kDa (ITGB2) based on Bis-Tris PAGE result.
Activity	Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human ITGAX&ITGB2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB2 Antibody, hFc Tag with the EC50 of 21.4ng/ml determined by ELISA (QC Test).
	Human ITGAX&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ITGAX&ITGB2 is greater than 95% as determined by SEC-HPLC.