Human Interferon omega-1 Protein (IFN-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Leu22-Ser195

Catalog: IFN-HM101

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Product Description Recombinant Human Interferon omega-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu22-Ser195.

Product Background

Human Interferon omega-1, a type I IFN, also known as IFN-ω1 or IFNW1, it contains a potential N-glycosylation site like human IFN-β. IFN-ω1 binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. All IFN-ω genes analysed to date are devoid of introns. IFN-ω1 has been shown to be well-tolerated in man and to induce reductions of hepatitis C virus RNA levels in a series of human clinical trials.

Product Category

Recombinant Protein

Target

Interferon omega-1
Accession

Species

Human

Amino Acid Range

Leu22-Ser195
Molecular Weight The protein has a predicted MW of 21.25 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human IFNAR1, His Tag immobilized on CM5 Chip can bind Human Interferon omega-1, His Tag with an affinity constant of 20.96 uM as determined in SPR assay (Biacore T200).
The purity of Human Interferon omega-1 is greater than 95% as determined by SEC-HPLC.
Human Interferon omega-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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