Human Interferon omega-1 Protein (IFN-HM101)
Human Interferon omega-1 Protein (IFN-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Leu22-Ser195
Catalog #IFN-HM101
Regular price $270.00
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Product Description

Recombinant Human Interferon omega-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu22-Ser195.

Product Background

Human Interferon omega-1, a type I IFN, also known as IFN-ω1 or IFNW1, it contains a potential N-glycosylation site like human IFN-β. IFN-ω1 binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. All IFN-ω genes analysed to date are devoid of introns. IFN-ω1 has been shown to be well-tolerated in man and to induce reductions of hepatitis C virus RNA levels in a series of human clinical trials.

Product Category

Recombinant Protein / Antibody discovery

Protein

Interferon omega-1

Synonyms

Interferon alpha-II-1; IFNW1; IFN-ω1; IFN-omega-1

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Leu22-Ser195

Molecular Weight

The protein has a predicted MW of 21.25 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human IFNAR1, His Tag immobilized on CM5 Chip can bind Human Interferon omega-1, His Tag with an affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). Human IFNAR1, His Tag immobilized on CM5 Chip can bind Human Interferon omega-1, His Tag with an affinity constant of 20.96 uM as determined in SPR assay (Biacore T200).
Human Interferon omega-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Interferon omega-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human Interferon omega-1 is greater than 95% as determined by SEC-HPLC. The purity of Human Interferon omega-1 is greater than 95% as determined by SEC-HPLC.

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