Human Interferon omega-1 Protein (IFN-HM101)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Leu22-Ser195

Catalog: IFN-HM101

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Product Description	Recombinant Human Interferon omega-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu22-Ser195.
Product Background	Human Interferon omega-1, a type I IFN, also known as IFN-ω1 or IFNW1, it contains a potential N-glycosylation site like human IFN-β. IFN-ω1 binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. All IFN-ω genes analysed to date are devoid of introns. IFN-ω1 has been shown to be well-tolerated in man and to induce reductions of hepatitis C virus RNA levels in a series of human clinical trials.
Product Category	Recombinant Protein

Target	Interferon omega-1
Gene/Protein ID	P05000
Species	Human
Exact Sequence	Leu22-Ser195
Molecular Weight	The protein has a predicted MW of 21.25 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
Activity	The affinity constant of 20.96 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human IFNAR1, His Tag immobilized on CM5 Chip can bind Human Interferon omega-1, His Tag with an affinity constant of 20.96 uM as determined in SPR assay (Biacore T200).
	The purity of Human Interferon omega-1 is greater than 95% as determined by SEC-HPLC.
	Human Interferon omega-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.