Name: Human ITCH Protein (ITH-HE001)
Brand: KactusBio
SKU: ITH-HE001-100UG
Price: 330.0 USD
Availability: InStock

Catalog #ITH-HE001

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Human ITCH Protein is expressed from E.coli without tag.It contains Arg485-Glu862.
Product Background	Itch or itchy E3 is a member of the homologous to E6-associated protein C-terminus (HECT)-type family of E3 ligases, with the protein-interacting WW-domains for the recruitment of substrate and the HECT domain for the transfer of ubiquitin to the substrate, and its deletion results in an itchy phenotype with constant skin scratching and multi-organ inflammation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	ITCH
Synonyms	AIP4; NAPP1; AIF4
Accession	NP_113671.3
Species	Human
Biotinylated	no
Amino Acid Range	Arg485-Glu862
Molecular Weight	The protein has a predicted MW of 44.98 kDa same as Bis-Tris PAGE result.
Product Tag	No Tag
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS, 200mM L-Arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human ITCH on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ITCH is greater than 90% as determined by SEC-HPLC.