Human ITK Protein (ITK-HB601)
  • Express System: Baculovirus-Insect Cells
  • Product Tag: N-GST
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Arg352-Leu620
Catalog #ITK-HB601
Regular price $345.00
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Product Description
Recombinant Human ITK Protein is expressed from Baculovirus-Insect Cells with GST tag at the N-terminus.It contains Arg352-Leu620.
Product Background
Itk/Emt, a tec family tyrosine kinase, is important for T-cell development and activation through the antigen receptor. Itk/Emt can induce the generation of important second signals (PKC, Ca2+) and can modulate their duration by maintaining the stability of scaffolding complexes through regulation of cytoskeletal reorganization.
Product Category
Recombinant Protein
Target
ITK
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Arg352-Leu620
Molecular Weight
The protein has a predicted MW of 57.33 kDa same as Bis-Tris PAGE result.
Product Tag
N-GST
Express System
Baculovirus-Insect Cells
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 50mM Tris, 150mM NaCl, 25% glycerol, 0.5mM PMSF, 0.5 mM TCEP, 0.1mM EDTA, 0.5mM GSH (pH 7.5).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human ITK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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