|Recombinant Human ITK Protein is expressed from Baculovirus-Insect Cells with GST tag at the N-terminus.It contains Arg352-Leu620.
|Itk/Emt, a tec family tyrosine kinase, is important for T-cell development and activation through the antigen receptor. Itk/Emt can induce the generation of important second signals (PKC, Ca2+) and can modulate their duration by maintaining the stability of scaffolding complexes through regulation of cytoskeletal reorganization.
|The protein has a predicted MW of 57.33 kDa same as Tris-Bis PAGE result.
|> 95% as determined by Tris-Bis PAGE
|Less than 1EU per ug by the LAL method.
|Shipped with dry ice.
|Supplied as 0.22 um filtered solution in 50mM Tris, 150mM NaCl, 25% glycerol, 0.5mM PMSF, 0.5 mM TCEP, 0.1mM EDTA, 0.5mM GSH (pH 7.5).
|Stability And Storage
|Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.