Product Description |
Recombinant Human ITK Protein is expressed from Baculovirus-Insect Cells with GST tag at the N-terminus.It contains Arg352-Leu620. |
Product Background |
Itk/Emt, a tec family tyrosine kinase, is important for T-cell development and activation through the antigen receptor. Itk/Emt can induce the generation of important second signals (PKC, Ca2+) and can modulate their duration by maintaining the stability of scaffolding complexes through regulation of cytoskeletal reorganization. |
Product Category |
Recombinant Protein |
Target |
ITK |
Synonyms |
Kinase EMT; ITK; EMT; LYK; T-cell-specific kinase; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Arg352-Leu620 |
Molecular Weight |
The protein has a predicted MW of 57.33 kDa same as Bis-Tris PAGE result. |
Product Tag |
N-GST |
Express System |
Baculovirus-Insect Cells |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 50mM Tris, 150mM NaCl, 25% glycerol, 0.5mM PMSF, 0.5 mM TCEP, 0.1mM EDTA, 0.5mM GSH (pH 7.5). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human ITK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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