Human ITK Protein (ITK-HB601)

  • Express System: Baculovirus-Insect Cells
  • Product Tag: N-GST
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Amino Acid Range: Arg352-Leu620

Catalog: ITK-HB601

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Product Description Recombinant Human ITK Protein is expressed from Baculovirus-Insect Cells with GST tag at the N-terminus.It contains Arg352-Leu620.

Product Background

 Itk/Emt, a tec family tyrosine kinase, is important for T-cell development and activation through the antigen receptor. Itk/Emt can induce the generation of important second signals (PKC, Ca2+) and can modulate their duration by maintaining the stability of scaffolding complexes through regulation of cytoskeletal reorganization.

Product Category

 Recombinant Protein

Target

 ITK
Accession

Species

 Human

Amino Acid Range

 Arg352-Leu620
Molecular Weight The protein has a predicted MW of 57.33 kDa same as Tris-Bis PAGE result.

Product Tag

 N-GST

Express System

 Baculovirus-Insect Cells
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in 50mM Tris, 150mM NaCl, 25% glycerol, 0.5mM PMSF, 0.5 mM TCEP, 0.1mM EDTA, 0.5mM GSH (pH 7.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human ITK on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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