Human JAM-A Protein (JAM-HM10A)
Human JAM-A Protein (JAM-HM10A)
Human JAM-A Protein (JAM-HM10A)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human JAM-A, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-JAM-A Antibody, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ser28-Val238.
Catalog #JAM-HM10A
Regular price $330.00
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Product Description

Recombinant Human JAM-A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser28-Val238.

Product Background

junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.

Product Category

Recombinant Protein / Antibody discovery

Protein

JAM-A

Synonyms

JAM-A; JAM-1; CD321; JAM; JCAM; JCAM1; KAT; PAM-1; F11 receptor; F11R; PAM-1KAT

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ser28-Val238.

Molecular Weight

The protein has a predicted MW of 24 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human JAM-A, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-JAM-A Antibody, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human JAM-A, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-JAM-A Antibody, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA. Immobilized Human JAM-A, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-JAM-A Antibody, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.
Human JAM-A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human JAM-A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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