Product Description |
Recombinant Human JAML Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Leu275. |
Product Background |
JAML (junctional adhesion molecule-like), contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail. JAML mRNA is expressed in hematopoietic tissues and is prominently expressed in granulocytes. The fact that JAML protein is localized at the cell plasma membrane in the areas of cell-cell contacts, whereas it is not detected at free cell borders, suggests that JAML is engaged in homophilic interactions. |
Product Category |
Recombinant Protein |
Target |
JAML |
Synonyms |
JunctioJAML; AMICA1; AMICA; CREA7-1; Gm638; JAML |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu20-Leu275 |
Molecular Weight |
The protein has a predicted MW of 30.1 kDa. Due to glycosylation, the protein migrates to 38-42 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human JAML on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human JAML is greater than 95% as determined by SEC-HPLC. |
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