Name: Human Kallikrein 11/KLK11 Protein (active form) (KLK-HM111)
Brand: KactusBio
SKU: KLK-HM111-100UG
Price: 375.0 USD
Availability: InStock

Human Kallikrein 11/KLK11 Protein (active form) (KLK-HM111)

Human Kallikrein 11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human Kallikrein 11 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Measured by its ability to cleave the fluorogenic peptide substrate: N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-Lys-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is > 1200pmol/min/µg.
Amino Acid Range: Ile54-Asn282
Other Available Proteins:

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Catalog #KLK-HM111

Size

100UG

500UG

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Human Kallikrein 11/KLK11 Protein (active form) (KLK-HM111) Summary

Product Description	Recombinant Human Kallikrein 11/KLK11 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile54-Asn282.
Product Background	Human kallikrein 11 (hK11/trypsin-like serine protease/TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases. Elevated serum hK11 levels were found in 60% of men with prostate cancer and 70% of women with ovarian cancer. Also, hK11 expression was found to be under the regulation of steroid hormones, particularly estrogens, at the level of KLK11 transcription.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Kallikrein 11/KLK11 Protein (active form) (KLK-HM111) Specifications/Details

Protein	Kallikrein 11/KLK11
Synonyms	Kallikrein-11; hK11; Hippostasin; KLK11; PRSS20; TLSP
Accession	Q9UBX7-2
Species	Human
Biotinylated	no
Amino Acid Range	Ile54-Asn282
Molecular Weight	The protein has a predicted MW of 26.85 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity	Measured by its ability to cleave the fluorogenic peptide substrate: N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-Lys-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is > 1200pmol/min/µg.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM HEPES, 150mM NaCl, 8% trehalose, 0.05% Brij-35 (pH 7.5).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human Kallikrein 11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Kallikrein 11 is greater than 95% as determined by SEC-HPLC.

Human Kallikrein 11/KLK11 Protein (active form) (KLK-HM111) Summary

Product Description

Product Background

Product Category

Human Kallikrein 11/KLK11 Protein (active form) (KLK-HM111) Specifications/Details

Fluorophore

Shipping, Reconstitution, & Storage

Validation Images

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