Human Kallikrein 11/KLK11 Protein (active form), Ultra Low Endotoxin (

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Measured by its ability to cleave the fluorogenic peptide substrate: N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-Lys-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is > 1200pmol/min/µg.
Amino Acid Range: Ile54-Asn282

Catalog #KLK-HM111-UL

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$412.50

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Human Kallikrein 11/KLK11 Protein (active form), Ultra Low Endotoxin (KLK-HM111-UL) Summary

Product Description	Recombinant Human Kallikrein 11/KLK11 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile54-Asn282.
Product Background	Human kallikrein 11 (hK11/trypsin-like serine protease/TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases. Elevated serum hK11 levels were found in 60% of men with prostate cancer and 70% of women with ovarian cancer. Also, hK11 expression was found to be under the regulation of steroid hormones, particularly estrogens, at the level of KLK11 transcription.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Kallikrein 11/KLK11
Synonyms	Kallikrein-11; hK11; Hippostasin; KLK11; PRSS20; TLSP
Accession	Q9UBX7-2
Species	Human
Biotinylated	no
Amino Acid Range	Ile54-Asn282
Molecular Weight	The protein has a predicted MW of 26.85 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity	Measured by its ability to cleave the fluorogenic peptide substrate: N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-Lys-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is > 1200pmol/min/µg.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM HEPES, 150mM NaCl, 8% trehalose, 0.05% Brij-35 (pH 7.5).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human Kallikrein 11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Kallikrein 11 is greater than 95% as determined by SEC-HPLC.

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