Human Kallikrein 12 Protein (active form) (KLK-HM112)

Express System: HEK293
Product Tag: C-His
Purity: > 90% as determined by Bis-Tris PAGE
Activity: Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >15000 pmol/min/ug.
Amino Acid Range: Ile22-Asn248

Catalog #KLK-HM112

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$420.00

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Human Kallikrein 12 Protein (active form) (KLK-HM112) Summary

Product Description	Recombinant Human Kallikrein 12 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile22-Asn248.
Product Background	Kallikrein-related peptidase 12 (KLK12, a member of the kallikrein-related peptidase family ranging from KLK1 to KLK15) is a secreted serine protease with trypsin-like activity. KLK12 is expressed in a large number of human organs and tissues, such as bone, bone marrow, the colon, the lung, the trachea, the prostate, the salivary glands, and the stomach. Expression of KLK12 is dysregulated in several diseases, including breast, gastric and lung cancers.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Protein	Kallikrein 12
Synonyms	Kallikrein-12; KLK-L5; KLK12; KLKL5
Accession	Q9UKR0-1
Species	Human
Biotinylated	no
Amino Acid Range	Ile22-Asn248
Molecular Weight	The protein has a predicted MW of 26.18 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity	Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >15000 pmol/min/ug.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM NaAC, 150mM NaCl, 8% trehalose, 0.05% Brij 35, 10mM Benzamidine (pH 5.0).
Reconstitution	Dissolve the lyophilized protein in 20mM NaAC (pH 5.0). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Human Kallikrein 12 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

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