- Express System: HEK293
- Product Tag: C-His
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Measured by its ability to cleave the fluorogenic peptide substrate Boc-Val-Pro-Arg-AMC. The specific activity is >1000 pmol/min/ug.
- Amino Acid Range: Val26-Gln277
Human Kallikrein 13/KLK13 Protein (active form) (KLK-HM113) Summary
Product Description |
Recombinant Human Kallikrein 13/KLK13 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Val26-Gln277. |
Product Background |
Kallikrein 13 (KLK13) is primarily expressed in the testis, prostate, breast, salivary glands, esophagus and the cervix and is associated with certain skin pathologies, including psoriasis vulgaris and atopic dermatitis. Moreover, KLK13 is expressed at high levels in some types of salivary gland tumors. Furthermore, it has been reported as an independent, favorable prognostic marker in breast and ovarian cancers and has potential clinical utility as a prediction marker of gastric cancer cells' response to chemotherapy. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human Kallikrein 13/KLK13 Protein (active form) (KLK-HM113) Specifications/Details
Protein |
Kallikrein 13/KLK13 |
Synonyms |
Kallikrein-13; KLK-L4; KLKL4; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Val26-Gln277 |
Molecular Weight |
The protein has a predicted MW of 39.18 kDa. Due to glycosylation, the protein migrates to 32-40 kDa based on Bis-Tris PAGE result. |
Activity |
Measured by its ability to cleave the fluorogenic peptide substrate Boc-Val-Pro-Arg-AMC. The specific activity is >1000 pmol/min/ug. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in 20mM NaAC, 150mM NaCl, 8% trehalose (pH 5.0). |
Reconstitution |
Dissolve the lyophilized protein in 20mM NaAC (pH 5.0). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins:
Finding available proteins...
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