Human Kallikrein 13/KLK13 Protein (active form) (KLK-HM113)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Measured by its ability to cleave the fluorogenic peptide substrate Boc-Val-Pro-Arg-AMC. The specific activity is >1200 pmol/min/ug.
  • Amino Acid Range: Val26-Gln277
Catalog #KLK-HM113
Regular price $375.00
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Human Kallikrein 13/KLK13 Protein (active form) (KLK-HM113) Summary

Product Description

Recombinant Human Kallikrein 13/KLK13 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Val26-Gln277.

Product Background

Kallikrein 13 (KLK13) is primarily expressed in the testis, prostate, breast, salivary glands, esophagus and the cervix and is associated with certain skin pathologies, including psoriasis vulgaris and atopic dermatitis. Moreover, KLK13 is expressed at high levels in some types of salivary gland tumors. Furthermore, it has been reported as an independent, favorable prognostic marker in breast and ovarian cancers and has potential clinical utility as a prediction marker of gastric cancer cells' response to chemotherapy.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human Kallikrein 13/KLK13 Protein (active form) (KLK-HM113) Specifications/Details

Protein
Kallikrein 13/KLK13
Synonyms
Kallikrein-13; KLK-L4; KLKL4;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Val26-Gln277
Molecular Weight
The protein has a predicted MW of 39.18 kDa. Due to glycosylation, the protein migrates to 32-40 kDa based on Bis-Tris PAGE result.
Activity
Measured by its ability to cleave the fluorogenic peptide substrate Boc-Val-Pro-Arg-AMC. The specific activity is >1200 pmol/min/ug.
Product Tag
C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in 20mM NaAC, 150mM NaCl, 8% trehalose (pH 5.0).
Reconstitution
Dissolve the lyophilized protein in 20mM NaAC, 150mM NaCl (pH 5.0). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human Kallikrein 13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Kallikrein 13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human Kallikrein 13 is greater than 95% as determined by SEC-HPLC. The purity of Human Kallikrein 13 is greater than 95% as determined by SEC-HPLC.
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