Name: Human Kallikrein 5/KLK5 Protein (active form) (KLK-HM605)
Brand: KactusBio
SKU: KLK-HM605-100UG
Price: 412.5 USD
Availability: InStock

Human Kallikrein 5/KLK5 Protein (active form) (KLK-HM605)

Human Kallikrein 5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human Kallikrein 5 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Flag
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Ile67-Ser293

Catalog #KLK-HM605

Size

100UG

500UG

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Product Description	Recombinant Human Kallikrein 5/KLK5 Protein is expressed from HEK293 with His tag and Flag tag at the C-terminus.It contains Ile67-Ser293.
Product Background	The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-discovery approaches.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Kallikrein 5/KLK5
Synonyms	Kallikrein c; Klnc; KLK5; KLKL2; KLK-L2; SCTE
Accession	Q9Y337
Species	Human
Biotinylated	no
Amino Acid Range	Ile67-Ser293
Molecular Weight	The protein has a predicted MW of 31.7 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Product Tag	C-His-Flag
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 50mM MES, 150mM NaCl (pH 5.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human Kallikrein 5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Kallikrein 5 is greater than 95% as determined by SEC-HPLC.