Name: Human Kallikrein 7/KLK7 Protein (active form) (KLK-HM007)
Brand: KactusBio
SKU: KLK-HM007-100UG
Price: 396.0 USD
Availability: InStock

Human Kallikrein 7/KLK7 Protein (active form) (KLK-HM007)

Immobilized Human Kallikrein 7, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kallikrein 7 Antibody, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA.

Human Kallikrein 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

Express System: HEK293
Product Tag: No Tag
Purity: > 90% as determined by Bis-Tris PAGE
Activity: Immobilized Human Kallikrein 7, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kallikrein 7 Antibody, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH₂. The specific activity is >350 pmol/min/µg.
Amino Acid Range: Ile30-Arg253

Catalog #KLK-HM007

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human Kallikrein 7/KLK7 Protein (active form) (KLK-HM007) Summary

Product Description	Recombinant Human Kallikrein 7/KLK7 Protein is expressed from HEK293 without tag.It contains Ile30-Arg253.
Product Background	Kallikrein 7 (KLK7) is a secreted serine protease with chymotrypsic protease activity. Abnormally high expression of KLK7 is closely related to the occurrence and development of various types of cancer. Therefore, KLK7 has been identified as a potential target for cancer drug development design in recent years. KLK7 mediates various biological and pathological processes in tumorigenesis, including cell proliferation, migration, invasion, angiogenesis, and cell metabolism, by hydrolyzing a series of substrates such as membrane proteins, extracellular matrix proteins, and cytokines.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Kallikrein 7/KLK7 Protein (active form) (KLK-HM007) Specifications/Details

Protein	Kallikrein 7/KLK7
Synonyms	Kallikrein-7; hK7; Serine protease 6; hSCCE; KLK7; PRSS6; SCCE
Accession	P49862
Species	Human
Biotinylated	no
Amino Acid Range	Ile30-Arg253
Molecular Weight	The protein has a predicted MW of 24.44 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Kallikrein 7, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kallikrein 7 Antibody, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH₂. The specific activity is >350 pmol/min/µg.
Product Tag	No Tag
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM HEPES, 150mM NaCl, 8% trehalose, 0.05% Brij-35, 5mM Benzamidine (pH 7.5).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human Kallikrein 7, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kallikrein 7 Antibody, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA.
	Human Kallikrein 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.