Human Kallikrein 7/KLK7 Protein (pro form) (KLK-HM617)
  • Express System: HEK293
  • Product Tag: C-His-Flag
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Glu23-Arg253
Catalog #KLK-HM617
Regular price $412.50
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Product Description

Recombinant Human Kallikrein 7/KLK7 Protein (pro form) is expressed from HEK293 with His tag and Flag tag at the C-terminus. The protein needs to be activated by Thermolysin for an activated form.It contains Glu23-Arg253.

Product Background

Kallikrein 7 (KLK7) is a secreted serine protease with chymotrypsic protease activity. Abnormally high expression of KLK7 is closely related to the occurrence and development of various types of cancer. Therefore, KLK7 has been identified as a potential target for cancer drug development design in recent years. KLK7 mediates various biological and pathological processes in tumorigenesis, including cell proliferation, migration, invasion, angiogenesis, and cell metabolism, by hydrolyzing a series of substrates such as membrane proteins, extracellular matrix proteins, and cytokines.

Product Category

Recombinant Protein / Antibody discovery

Protein

Kallikrein 7/KLK7

Synonyms

Kallikrein-7; hK7; Serine protease 6; hSCCE; KLK7; PRSS6; SCCE

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Glu23-Arg253

Molecular Weight

The protein has a predicted MW of 27.29 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.

Product Tag

C-His-Flag

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC

Endotoxin

Less than 0.1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 20mM HEPES, 150mM NaCl (pH 7.5).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human Kallikrein 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Kallikrein 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human Kallikrein 7 is greater than 90% as determined by SEC-HPLC. The purity of Human Kallikrein 7 is greater than 90% as determined by SEC-HPLC.

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