Name: Human Kallikrein 8/KLK8 Protein (active form) (KLK-HM108)
Brand: KactusBio
SKU: KLK-HM108-100UG
Price: 375.0 USD
Availability: InStock

Human Kallikrein 8/KLK8 Protein (active form) (KLK-HM108)

Human Kallikrein 8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human Kallikrein 8 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Measured by its ability to cleave the fluorogenic peptide substrate: BOC-Val-Pro-Arg-AMC. The specific activity is >500 pmol/min/ug.
Amino Acid Range: Val33-Gly260
Other Available Proteins:

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Catalog #KLK-HM108

Size

100UG

500UG

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Human Kallikrein 8/KLK8 Protein (active form) (KLK-HM108) Summary

Product Description	Recombinant Human Kallikrein 8/KLK8 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Val33-Gly260.
Product Background	Neuropsin (NP, kallikrein 8, KLK8) - a kallikrein gene-related (KLK) endoprotease - plays a key role in neuroplasticity processes, since intracellular signal cascades and regulation of gene expression are engaged in long-term synaptic plasticity. Neuropsin is a type of serine proteases, which are involved in extracellular proteolysis. Serine proteases belong to the class of hydrolases, subclass of proteases, and are in charge of selective catalysis of peptide bond hydrolysis.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Kallikrein 8/KLK8 Protein (active form) (KLK-HM108) Specifications/Details

Protein	Kallikrein 8/KLK8
Synonyms	hK8; Kallikrein-8; Neuropsin; Ovasin; NRPN; PRSS19; TADG14; KLK8
Accession	O60259-1
Species	Human
Biotinylated	no
Amino Acid Range	Val33-Gly260
Molecular Weight	The protein has a predicted MW of 26.07 kDa. Due to glycosylation, the protein migrates to 32-38 kDa based on Bis-Tris PAGE result.
Activity	Measured by its ability to cleave the fluorogenic peptide substrate: BOC-Val-Pro-Arg-AMC. The specific activity is >500 pmol/min/ug.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM HEPES, 150mM NaCl, 8% trehalose, 0.05% Brij-35, 5mM Benzamidine (pH 7.5).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human Kallikrein 8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Kallikrein 8 is greater than 95% as determined by SEC-HPLC.

Human Kallikrein 8/KLK8 Protein (active form) (KLK-HM108) Summary

Product Description

Product Background

Product Category

Human Kallikrein 8/KLK8 Protein (active form) (KLK-HM108) Specifications/Details

Fluorophore

Shipping, Reconstitution, & Storage

Validation Images

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