Name: Human Kremen-1 Protein (KRE-HM201)
Brand: KactusBio
SKU: KRE-HM201-100UG
Price: 412.5 USD
Availability: InStock

Catalog #KRE-HM201

Size

100UG

500UG

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Product Description	Recombinant Human Kremen-1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Arg21-Thr392.
Product Background	KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.
Product Category	Recombinant Protein / Antibody discovery

Protein	Kremen-1
Synonyms	Kremen protein 1; KREMEN; KRM1; KREMEN1
Accession	Q96MU8-1
Species	Human
Biotinylated	no
Amino Acid Range	Arg21-Thr392
Molecular Weight	The protein has a predicted MW of 67.6 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human Kremen-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Kremen-1 is greater than 95% as determined by SEC-HPLC.