Name: Human Kremen-2 Protein (KRE-HM102)
Brand: KactusBio
SKU: KRE-HM102-100UG
Price: 379.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Kremen-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gly26-Ala364

Catalog #KRE-HM102

Size

100UG

500UG

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Product Description	Recombinant Human Kremen-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly26-Ala364.
Product Background	Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Kremen-2
Synonyms	KRM2; KREMEN2; Kremen-2; Dickkopf receptor 2
Accession	Q8NCW0-1
Species	Human
Biotinylated	no
Amino Acid Range	Gly26-Ala364
Molecular Weight	The protein has a predicted MW of 37.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Kremen-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Kremen-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA (QC Test).
	Human Kremen-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Kremen-2 is greater than 95% as determined by SEC-HPLC.