- Express System: HEK293
- Purity: > 95% as determined by HPLC
- Activity: Immobilized Human Kv1.3 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kv1.3 Antibody, hFc Tag with the EC50 of 1.4ng/ml determined by ELISA.
- Amino Acid Range: Met1-Val575
Human Kv1.3 VLP (KV1-HM00V) Summary
Product Description |
Recombinant Human Kv1.3 VLP is expressed from HEK293.It contains Met1-Val575 (It may have cross reaction with anti-His antibody). |
Product Background |
Kv1.3 is a voltage gated potassium channel located in the plasma membrane, as well as at intracellular levels, such as mitochondria (mitoKv1.3), nucleus and Golgi apparatus. The plasma membrane channel has been shown to be important for cell proliferation, while the mitochondrial counterpart has been related to modulation of cell death. Moreover, altered expression of Kv1.3 was observed in various tumors and Kv1.3 seems to be involved in development and progression of various cancerous forms. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Human Kv1.3 VLP (KV1-HM00V) Specifications/Details
Protein |
Kv1.3 |
Synonyms |
HGK5; HLK3; HPCN3; KCNA3 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val575 |
Molecular Weight |
The target protein has a predicted MW of 94.06 kDa. |
Activity |
Immobilized Human Kv1.3 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kv1.3 Antibody, hFc Tag with the EC50 of 1.4ng/ml determined by ELISA. |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 300mM L-Arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins:
Finding available proteins...
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