Name: Human L1CAM Protein (LAM-HM101)
Brand: KactusBio
SKU: LAM-HM101-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human L1CAM, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-L1CAM Antibody, hFc Tag with the EC50 of 3.7ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ile20-Glu1120

Catalog #LAM-HM101

Size

100UG

500UG

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Product Description	Recombinant Human L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile20-Glu1120.
Product Background	L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
Product Category	Recombinant Protein / Antibody discovery

Protein	L1CAM
Synonyms	N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; CALL; CHL1; CHL-1; FLJ44930; L1CAM-2; MGC132578; HSAS; HSAS1; MASA; S10; SPG1
Accession	P32004-1
Species	Human
Biotinylated	no
Amino Acid Range	Ile20-Glu1120
Molecular Weight	The protein has a predicted MW of 124.6 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human L1CAM, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-L1CAM Antibody, hFc Tag with the EC50 of 3.7ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human L1CAM, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-L1CAM Antibody, hFc Tag with the EC50 of 3.7ng/ml determined by ELISA.
	Human L1CAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human L1CAM is greater than 95% as determined by SEC-HPLC.