Human LAG3/CD223 Protein (LAG-HM231)
Human LAG3/CD223 Protein (LAG-HM231)
Human LAG3/CD223 Protein (LAG-HM231)
Human LAG3/CD223 Protein (LAG-HM231)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human FGL1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LAG3, hFc Tag with the EC50 of 75.1ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu23-Leu450
Catalog #LAG-HM231
Regular price $270.00
/
Size

Order now, ships by:

Product Description
Recombinant Human LAG3/CD223 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Leu450.
Product Background
LAG-3, is a protein which in humans is encoded by the LAG3 gene, which is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders.
Product Category
Recombinant Protein
Target
LAG3/CD223
Synonyms
CD223; FDC; LAG3; LAG-3; sLAG-3
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Leu23-Leu450
Molecular Weight
The protein has a predicted MW of 72.4 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human FGL1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LAG3, hFc Tag with the EC50 of 75.1ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human FGL1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LAG3, hFc Tag with the EC50 of 75.1ng/ml determined by ELISA.
Human LAG3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed