Name: Human LAP (TGF beta 1) Protein (LAP-HM4B1)
Brand: KactusBio
SKU: LAP-HM4B1-100UG
Price: 405.0 USD
Availability: InStock

Human LAP (TGF beta 1) Protein (LAP-HM4B1)

Immobilized Human LAP (TGF beta 1), His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, His Tag with the EC50 of 0.52 ug/ml determined by ELISA.

Human LAP (TGF beta 1) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: N-His
Purity: >95% as determined by Bis-Tris PAGE
Activity: Immobilized Human LAP (TGF beta 1), His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, His Tag with the EC50 of 0.52 ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Leu30-Arg278(C33S)

Catalog #LAP-HM4B1

Size

100UG

500UG

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Product Description	Recombinant Human LAP (TGF beta 1) Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Leu30-Arg278(C33S).
Product Background	Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.
Product Category	Recombinant Protein / Antibody discovery

Protein	LAP (TGF beta 1)
Synonyms	CEDLAP; DPD1; TGF beta1; TGFB; TGFB1; TGFbeta; TGF-beta-1; TGF β1; TGFβ; TGF-β-1
Accession	P01137
Species	Human
Biotinylated	no
Amino Acid Range	Leu30-Arg278(C33S)
Molecular Weight	The protein has a predicted MW of 31.4 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human LAP (TGF beta 1), His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, His Tag with the EC50 of 0.52 ug/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human LAP (TGF beta 1), His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, His Tag with the EC50 of 0.52 ug/ml determined by ELISA.
	Human LAP (TGF beta 1) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.