Name: Human Latent GDF-11 Protein (GDF-HM111)
Brand: KactusBio
SKU: GDF-HM111-100UG
Price: 495.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Latent GDF-11, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF11 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.
Amino Acid Range: Ala25-Ser407
Other Available Proteins:

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Catalog #GDF-HM111

Size

100UG

500UG

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Human Latent GDF-11 Protein (GDF-HM111) Summary

Product Description	Recombinant Human Latent GDF-11 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala25-Ser407.
Product Background	Growth differentiation factor-11 (GDF-11), also known as bone morphogenetic protein-11, belongs to the transforming growth factor-beta superfamily. GDF-11 is highly related to MSTN, plays multiple roles during embryonic development, including regulating development of the axial skeleton, kidneys, nervous system, and pancreas.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Latent GDF-11 Protein (GDF-HM111) Specifications/Details

Protein	GDF-11
Synonyms	GDF11; BMP-11;
Accession	O95390
Species	Human
Biotinylated	no
Amino Acid Range	Ala25-Ser407
Molecular Weight	The protein has a predicted MW of 44.14 kDa. Due to glycosylation, the protein migrates to 15-20 kDa, 40-45 kDa and 50-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Latent GDF-11, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF11 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Latent GDF-11, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF11 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.
	Immobilized Human Latent GDF-11, His Tag at 2ug/ml(100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 11.2ng/ml determined by ELISA.
	Human Latent GDF-11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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