Name: Human Latent GDF-8 Protein (GDF-HM108)
Brand: KactusBio
SKU: GDF-HM108-100UG
Price: 363.0 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Human Latent GDF-8, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 22.8 ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Asn24-Ser375

Catalog #GDF-HM108

Size

100UG

500UG

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Product Description	Recombinant Human Latent GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn24-Ser375.
Product Background	Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.
Product Category	Recombinant Protein / Antibody discovery

Protein	Latent GDF-8
Synonyms	Myostatin; GDF8; Latent GDF8; Mstn
Accession	O14793
Species	Human
Biotinylated	no
Amino Acid Range	Asn24-Ser375
Molecular Weight	The protein has a predicted MW of 41.19 kDa. Due to glycosylation, the protein migrates to 35-40 kDa and 45-55 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Latent GDF-8, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 22.8 ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS / PBS, 200mM L-Arginine (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Latent GDF-8, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 22.8 ng/ml determined by ELISA (QC Test).
	Human Latent GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Latent GDF-8 is greater than 95% as determined by SEC-HPLC.