Human LAYN Protein (LAY-HM101)
Human LAYN Protein (LAY-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala22-Leu235
Catalog #LAY-HM101
Regular price $270.00
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Product Description
Recombinant Human LAYN Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-Leu235.
Product Background
Layilin (LAYN) is a critical gene that regulates T cell function. LAYN is correlated with prognosis and immune infiltrating levels of, including those of CD8 T cells, CD4 T cells, macrophages, neutrophils, and DCs in multiple cancers, especially in colon and gastric cancer patients. In addition, LAYN expression potentially contributes to regulation of tumor-associated macrophages (TAMs), DCs, T cell exhaustion and Tregs in colon and gastric cancer.
Product Category
Recombinant Protein
Target
LAYN
Synonyms
Layilin; FLJ30977; FLJ31092; LAYN; LYAN
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ala22-Leu235
Molecular Weight
The protein has a predicted MW of 25.4 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human LAYN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human LAYN is greater than 95% as determined by SEC-HPLC.

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