Product Description |
Recombinant Human LAYN Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-Leu235. |
Product Background |
Layilin (LAYN) is a critical gene that regulates T cell function. LAYN is correlated with prognosis and immune infiltrating levels of, including those of CD8 T cells, CD4 T cells, macrophages, neutrophils, and DCs in multiple cancers, especially in colon and gastric cancer patients. In addition, LAYN expression potentially contributes to regulation of tumor-associated macrophages (TAMs), DCs, T cell exhaustion and Tregs in colon and gastric cancer. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
LAYN |
Synonyms |
Layilin; FLJ30977; FLJ31092; LAYN; LYAN |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala22-Leu235 |
Molecular Weight |
The protein has a predicted MW of 25.4 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human LAYN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human LAYN is greater than 95% as determined by SEC-HPLC. |
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