Human LGR-4 Protein-Nanodisc (LGR-HM10N)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). The affinity constant of 0.40 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Ala25-Asp951
Catalog #LGR-HM10N
Regular price $1,100.00
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Product Description

Recombinant Human LGR-4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Ala25-Asp951.

Product Background

Leucine-rich repeat-containing G protein-coupled receptor (LGR)-4 is a G protein-coupled receptor (GPCR) with a seven-transmembrane domain structure. LGRs are evolutionally and structurally phylogenetic, classified into three subgroups and are members of the so-called orphan receptors.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein

LGR-4

Synonyms

LGR4; GPR48

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ala25-Asp951

Molecular Weight

The protein has a predicted MW of 105.80 kDa.

Activity

Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). The affinity constant of 0.40 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human R Spondin 3, His Tag immobilized on CM5 Chip can bind Human LGR-4 Nanodisc, His Tag with an affinity constant of 0.40 nM as determined in SPR assay (Biacore T200). Human R Spondin 3, His Tag immobilized on CM5 Chip can bind Human LGR-4 Nanodisc, His Tag with an affinity constant of 0.40 nM as determined in SPR assay (Biacore T200).
Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test).

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