Human LGR-5 VLP (LGR-HM00V)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human LGR-5 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LGR-5 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA.
Amino Acid Range: Met1-Leu907

Catalog #LGR-HM00V

Price

$1,235.00

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Human LGR-5 VLP (LGR-HM00V) Summary

Product Description	Recombinant Human LGR-5 VLP is expressed from HEK293.It contains Met1-Leu907 (It may have cross reaction with anti-His antibody).
Product Background	G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Protein	LGR-5
Synonyms	LGR5; GPR49; GPR67; HG38; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38
Accession	O75473-1
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Leu907
Molecular Weight	The target protein has a predicted MW of 101.03 kDa.
Activity	Immobilized Human LGR-5 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LGR-5 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA.
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human LGR-5 VLP at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LGR-5 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA.
	The purity of Human LGR-5 VLP is greater than 95% as determined by SEC-HPLC.

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