Human LILRA1/CD85i/LIR-6 Protein (LIL-HM4A1)
Catalog: LIL-HM4A1
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| Product Description | Recombinant Human LILRA1/CD85i/LIR-6 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Pro17-Asn461. |
Product Background |
LILRA1, also known as CD85i and LIR-6, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA1 consists of a 445 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 7 aa cytoplasmic tail. LILRA1 may act as receptor for class I MHC antigens. |
Product Category |
Recombinant Protein |
Target |
LILRA1/CD85i/LIR-6 |
| Synonyms | CD85i; LILRA1; LIR6; LIR-6; LIR6MGC126563 |
Gene/Protein ID |
O75019-1 |
Species |
Human |
Exact Sequence |
Pro17-Asn461 |
| Molecular Weight | The protein has a predicted MW of 51.4 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human LILRA1 is greater than 95% as determined by SEC-HPLC. |
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Human LILRA1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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