Name: Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein (LB4-HM4D4)
Brand: KactusBio
SKU: LB4-HM4D4-100UG
Price: 525.0 USD
Availability: InStock

Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein (LB4-HM4D4)

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gln22-Lys123

Catalog #LB4-HM4D4

Size

100UG

500UG

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Product Description	Recombinant Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Lys123.
Product Background	LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Product Category	Recombinant Protein

Target	LILRB4/CD85k/ILT3 Domain 1+hinge
Accession	AAH26309.1
Species	Human
Biotinylated	no
Amino Acid Range	Gln22-Lys123
Molecular Weight	The protein has a predicted MW of 14.77 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human LILRB4 Domain 1+hinge on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human LILRB4 Domain 1+hinge is greater than 95% as determined by SEC-HPLC.

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