Name: Human LY6G6D Protein (LYD-HM1GD)
Brand: KactusBio
SKU: LYD-HM1GD-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human LY6G6D, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Asn20-Ser104

Catalog #LYD-HM1GD

Size

100UG

500UG

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Human LY6G6D Protein (LYD-HM1GD) Summary

Product Description	Recombinant Human LY6G6D Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asn20-Ser104.
Product Background	LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human LY6G6D Protein (LYD-HM1GD) Specifications/Details

Protein	LY6G6D
Synonyms	Protein Ly6-D; C6orf23; G6D; MEGT1; NG25
Accession	O95868
Species	Human
Biotinylated	no
Amino Acid Range	Asn20-Ser104
Molecular Weight	The protein has a predicted MW of 10.20 kDa. Due to glycosylation, the protein migrates to 13-20 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human LY6G6D, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human LY6G6D, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA.
	Human LY6G6D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-LY6G6D Antibody, hFc-Avi Tag on ProA-Biosensor can bind Human LY6G6D, His Tag with an affinity constant of 2.48 nM as determined in BLI assay (Gator® Prime).