Human LY6G6D Protein (LYD-HM1GD)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human LY6G6D, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Asn20-Ser104

Catalog: LYD-HM1GD

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Product Description Recombinant Human LY6G6D Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asn20-Ser104.

Product Background

LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.

Product Category

Recombinant Protein

Target

LY6G6D
Accession

Species

Human

Exact Sequence

Asn20-Ser104
Molecular Weight The protein has a predicted MW of 10.20 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human LY6G6D, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human LY6G6D, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.9ng/ml determined by ELISA.
The purity of Human LY6G6D is greater than 95% as determined by SEC-HPLC.
Human LY6G6D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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