Human LYPD3 Protein (LPD-HM103)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human LYPD3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Leu31-His286

Catalog: LPD-HM103

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Product Description	Recombinant Human LYPD3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-His286.
Product Background	Aberrant expression of LYPD3 plays an oncogenic role in several types of cancer. LYPD3 was highly expressed in LUAD tumor compared with paracancerous tissues.Furthermore, the expression of LYPD3 was able to be regulated by the methylation in LYPD3 promoter region, which was positively associated with the overall survival. LYPD3 might affect the clinical manifestations of LUAD by regulating the P53 signaling pathway.
Product Category	Recombinant Protein

Target	LYPD3
Synonyms	MIG-C4; LYPD3; C4.4A; LY6/PLAUR domain containing 3
Accession	O95274
Species	Human
Amino Acid Range	Leu31-His286
Molecular Weight	The protein has a predicted MW of 27.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human LYPD3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human LYPD3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test).
	The purity of Human LYPD3 is greater than 95% as determined by SEC-HPLC.
	Human LYPD3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.