- Express System: HEK293
- Product Tag: C-His
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Immobilized Human LYPD3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test).
- Amino Acid Range: Leu31-His286
Human LYPD3 Protein (LPD-HM103) Summary
Product Description |
Recombinant Human LYPD3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-His286. |
Product Background |
Aberrant expression of LYPD3 plays an oncogenic role in several types of cancer. LYPD3 was highly expressed in LUAD tumor compared with paracancerous tissues.Furthermore, the expression of LYPD3 was able to be regulated by the methylation in LYPD3 promoter region, which was positively associated with the overall survival. LYPD3 might affect the clinical manifestations of LUAD by regulating the P53 signaling pathway. |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Human LYPD3 Protein (LPD-HM103) Specifications/Details
Protein |
LYPD3 |
Synonyms |
MIG-C4; LYPD3; C4.4A; LY6/PLAUR domain containing 3 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu31-His286 |
Molecular Weight |
The protein has a predicted MW of 27.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human LYPD3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test). |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
Other Available Proteins:
Finding available proteins...
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