Human HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein (MHC-HM427)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gly25-Thr305(HLA-A*01:01),Ile21-Met119(B2M)and EVDPIGHLY peptide

Catalog: MHC-HM427

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Product Description Recombinant Human MAGE-A3(HLA-A*01:01) Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*01:01),Ile21-Met119(B2M) and EVDPIGHLY peptide.

Product Background

Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.

Product Category

Recombinant Protein

Target

HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer
MHC Form Monomer
Allele HLA-A*01:01

Gene/Protein ID

Q5SUL5(HLA-A*01:01)&P61769(B2M)&EVDPIGHLY

Species

Human

Exact Sequence

Gly25-Thr305(HLA-A*01:01),Ile21-Met119(B2M)and EVDPIGHLY peptide
Molecular Weight The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

Product Tag

C-His-Avi

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer is greater than 95% as determined by SEC-HPLC.
Human HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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